Page 9 - PowerPoint Presentation

Hypermetabolism develops due to secretion of
stress hormones, such as cortisol, catecholamines

and glucagon. Profound catabolism, due to

suppression of anabolic hormones such as growth
hormones and insulin, results in muscle protein

breakdown. Clinically, patients may have

tachycardia, hyperthermia and muscle wasting.

Immunosuppression, bacterial translocation from

intestine, acute lung injury (Acute Respiratory

Distress Syndrome), concomitant inhalational
injury may also lead to sepsis, shock or even

mortality