Page 9 - PowerPoint Presentation

Ultraviolet light damage

 Direct photochemical damage to

cutaneous DNA

 Injury to DNA repair mechanism

 Partial suppression of cell-mediated

immunity

 Role of melanin in skin

Can absorb UV, i.e. photoprotective

Scavenges reactive oxygen species

which is linked with carcinogenesis

 Fairer skin more prone to developing

melanoma due to less melanin

 In 2009, the WHO's International Agency for

Research on Cancer (IARC) listed UV

radiation and indoor tanning beds as Class I

carcinogens.