Page 42 - PowerPoint Presentation

Extramammary Paget’s

disease

 An uncommon intra-epidermal carcinoma of
apocrine gland-bearing skin

 The most frequently involved anatomical sites

include the scrotum, penis, vulva, axilla and perineal
and perianal region

 Potential of dermal invasion

 Regional lymph node / distant metastasis

 Association with carcinoma of bladder, colon,

kidney and prostate.

Chan JY et al. Int J Surg. Oncol. 2012; 2012:416418

 The commonest presenting symptom is pruritis

 Features: erythematous, weepy and scaly

 Mimic eczema, psoriasis, Bowen’s disease, tinea cruris,
etc

 High index of suspicious is necessary in persistent
lesions and requires biopsy for definitive diagnosis

 Complete surgical resection with intra-operartive
frozen section for control of margins is the treatment

of choice