Page 16 - PowerPoint Presentation

Dermatofibrosarcoma

protuberance (DFSP)

 An uncommon tumour of dermal fibroblasts.

 Intermediate malignant potential.

 Locally aggressive tumour but seldom

metastasizes (<5%).

 Occurs primarily in adults aged 20-50s

 Distribution: majority over trunk and limbs,

followed by head and neck area

 Clinical features

 Usually appears as a slow-growing red solitary

cutaneous nodule

 The overlying epidermis is usually normal as the
tumour is arising from the dermal layer of the skin

 May mimic scar

 Biopsy is warranted for diagnosis

 Spindle cells arranged in an irregularly storiform,

cartwheel pattern extending from dermo-

epidermal junction into subcutaneous tissues

 Stains positively for CD34