Page 17 - PowerPoint Presentation

 Excision with at least 3cm radial margin

 Local recurrence is common if inadequately

excised

 Potential of fibrosarcomatous transformation

 Imatinib (selective tyrosine kinase inhibitor)

may be offered for those with unresectable

disease

 More than 90% have a reciprocal

chromosomal translocation t(17:22), that

leads to activation of PDGF receptor